Thermo Fisher Scientific TG Monoclonal Antibody (OTI8D5), TrueMAB
인체 Thyroglobulin(TG)을 표적으로 하는 마우스 모노클론 항체. IHC(P)에서 1:150 희석으로 검증됨. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 완충액에 보관. 갑상선 관련 연구용으로 적합하며 연구용 전용 제품.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8D5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–358 of human TG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Thyroid disorders often have autoimmune origins, and anti-thyroglobulin autoantibodies are key markers. Anti-hTG is present in all thyroid autoimmune diseases such as Hashimoto thyroiditis and Graves disease, with the highest levels observed in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer and can be used for monitoring cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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