Thermo Fisher Scientific Phospho-RET (Tyr1015) Polyclonal Antibody
RET 단백질의 Tyr1015 인산화 부위를 인식하는 폴리클로날 항체. Western blot에 최적화되어 있으며, 신경능선 발달 및 종양 관련 RET 신호 연구에 적합. 1 mg/mL 액상, -20°C 보관, 연구용 전용 제품.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human RET around the phosphorylation site of Tyr1015 (R-D-YP-L-D) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554927 |
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. RET transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia types IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET, but their biological validity has not been confirmed.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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