Thermo Fisher Scientific TAG1 Polyclonal Antibody
TAG1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, 고순도 Protein A 정제 및 안정적인 액상 형태로 제공됩니다. 신경 발달 연구용으로 최적화된 항체입니다.
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Thermo Fisher Scientific TAG1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human TAG1, amino acids 161–260 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system.
It is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunoglobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains.
Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts to guide commissural axons without promoting their growth.
It binds with NgCAM in the same membrane (cis-binding).
Heterophilic binding sites (Contactin 2/NgCAM and Contactin 2/NrCAM) are localized to the first four Ig domains, while the homophilic binding site (Contactin 2/Contactin 2) is localized to the FNIII domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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