Thermo Fisher Scientific PER3 Polyclonal Antibody
Human PER3 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:200~1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 생체 리듬 관련 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PER3. Recombinant protein control fragment (Product #RP-91592) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2645390 |
Product Specific Information
Immunogen sequence:
QPVHVSVSSG YGSLGSSGSQ EQLVSIASSS EASGHRVEET KAEQMTLQQV YASVNKIKNL GQQLYIESMT KSSFKPVTGT RTEPNGGGES ANGGGECKTF TSFHQTLKNN SVYTEPCEDL RNDEHSPSYQ QIN
Highest antigen sequence identity to the following orthologs:
- Mouse: 64%
- Rat: 66%
Target Information
This gene belongs to the Period family and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain.
Genes in this family regulate circadian rhythms of locomotor activity, metabolism, and behavior.
PER3 is upregulated by CLOCK/ARNTL heterodimers and represses this activity via PER/CRY heterodimers.
Polymorphisms in PER3 are associated with sleep disorders.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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