Thermo Fisher Scientific AGFG1 Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Immunogen sequence:
PQSTATANFA NFAHFNSHAA QNSANADFAN FDAFGQSSGS SNFGGFPTAS HSPFQPQTTG GSAASVNANF AHFDNFPKSS SADFGTFNTS QSHQTASAVS KVSTNKAGLQ TADKYAALAN LDNIFSAG

Antigen sequence identity:

• Mouse: 97%
• Rat: 94%

Target Information

HRB is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. HRB binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. The protein encoded by this gene is related to nucleoporins, which mediate nucleocytoplasmic transport. It binds the Rev activation domain when Rev is assembled onto its RNA target and can significantly enhance Rev activity when overexpressed. Several alternatively spliced transcript variants of this gene have been described, though the full-length nature of some variants has not been determined.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.