Thermo Fisher Scientific CYP4Z1 Polyclonal Antibody
CYP4Z1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합하며 인간, 마우스, 랫트 반응성. 액상 형태로 -20°C 보관, 1 mg/mL 농도, 연구용 전용.
- 판매단위
- pk
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Thermo Fisher Scientific CYP4Z1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) (IHC-P): 1:50–1:200
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CYP4Z1 (Accession Q86W10), corresponding to amino acid residues V80–G130 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850757 |
Product Specific Information
This antibody detects endogenous levels of total Cytochrome P450 4Z1.
Target Information
The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems that metabolize the fatty acid arachidonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenases requiring cofactors such as NADPH and P450 reductase.
Over 200 known genes encode P450s. Epoxygenases metabolize AA to epoxyeicosatrienoic acids (EETs), while omega-hydroxylases produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE).
In addition to fatty acid metabolism, P450s also metabolize drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids, and rifampicin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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