Thermo Fisher Scientific XRCC6BP1 Monoclonal Antibody (OTI5F3), TrueMAB
Thermo Fisher의 XRCC6BP1 단클론 항체(OTI5F3)는 인간 시료에 반응하며 Western blot과 IHC(P) 실험에 적합합니다. E. coli에서 발현된 full-length human XRCC6BP1 단백질로 면역화되었으며, 액상 형태로 제공되어 안정적인 실험 재현성을 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F3 |
| Immunogen | Full length human recombinant protein of human XRCC6BP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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