Thermo Fisher Scientific CDC42BPA Monoclonal Antibody (OTI7B9), TrueMAB
CDC42BPA 단백질을 인식하는 Monoclonal Antibody로, Western Blot에 최적화되어 있습니다. Human, Mouse, Rat에 반응하며, Lyophilized 형태로 제공됩니다. PBS 기반 완충액에 trehalose 포함, -20°C에서 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7B9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1419–1638 of human CDC42BPA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CDC42BPA (MRCKA) is a serine/threonine kinase involved in actin cytoskeleton assembly and organization.
It contains three independent coiled-coil domains and an N-terminal region preceding the kinase domain, enabling intermolecular interactions and MRCK alpha multimerization.
Transautophosphorylation regulates MRCK alpha catalytic activity. Binding of phorbol esters releases autoinhibition, allowing N-terminal dimerization and kinase activation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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