Thermo Fisher Scientific TOR2A Polyclonal Antibody
TOR2A 단백질을 표적으로 하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. Human 시료에 반응하며, Protein A로 정제된 액상 형태입니다. PBS(2% sucrose) 버퍼에 보관되며, -20°C에서 보존이 권장됩니다.
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Applications
- Western Blot (WB): Tested dilution 1.25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human TOR2A (aa 51–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607512 |
Product Specific Information
- Peptide sequence: GLECDLAQHL AGQHLAKALV VKALKAFVRD PAPTKPLVLS LHGWTGTGKS
- Sequence homology:
- Cow: 100%
- Dog: 100%
- Guinea Pig: 100%
- Horse: 93%
- Human: 100%
- Mouse: 100%
- Rat: 100%
Target Information
Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids.
Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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