Thermo Fisher Scientific TRAcP (Tartrate-Resistant Acid Phosphatase) Monoclonal Antibody (ACP5, 1070)
인간, 생쥐, 랫드 시료에 반응하는 TRAcP 단일클론 항체로, 포르말린 고정 조직의 IHC(P) 분석에 적합합니다. 단백질 A/G로 정제된 액상 항체이며, 4°C에서 보관합니다. 골대사 및 골흡수 연구에 활용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ACP5, 1070 |
| Immunogen | Recombinant full-length human ACP5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity towards phosphoproteins, ATP, and 4-nitrophenyl phosphatase.
It is detected in human alveolar macrophages, osteoclasts, spleen, and liver.
Expression is increased in:
- Spleen and monocytes of patients with Gaucher’s disease
- Spleenocytes and circulating leukocytes of patients with hairy cell leukemia
- Spleen of patients with Hodgkin’s lymphoma
- Sera of patients undergoing active bone turnover
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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