Thermo Fisher Scientific MYOZ1 Monoclonal Antibody (OTI8A1), TrueMAB
MYOZ1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI8A1). Western blot에 최적화되어 있으며, 인간 시료에 반응합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 106–299 of human MYOZ1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that extends half the length of a sarcomere and serves as a scaffold for myofibrils and other muscle-related proteins.
The MYOZ1 gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and acts as a substrate of titin kinase, interactions thought to be critical for sarcomere assembly.
Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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