Thermo Fisher Scientific PCDHB16 Monoclonal Antibody (3F12-2A6)
인간 PCDHB16 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 ELISA에 적합합니다. Affinity chromatography로 정제된 액상 형태이며, PBS(pH 7.4) 버퍼에 보존제 없이 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific PCDHB16 Monoclonal Antibody (3F12-2A6)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F12-2A6 |
| Immunogen | PCDHB16 (AAH36062.1, 1–776 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MEIGWMHNRR QRQVLVFFVL LSLSGAGAEL GSYSVVEETE RGSFVANLGK DLGLGLTEMS TRKARIISQG NKQHLQLKAQ TGDLLINEKL DREELCGPTE PCILHFQVLM ENPLEIFQAE LRVIDINDHS PMFTEKEMIL KIPENSPLGT EFPLNHALDL DVGSNNVQNY KISPSSHFRV LIHEFRDGRK YPELVLDKEL DREEEPQLRL TLTALDGGSP PRSGTAQVRI EVVDINDNAP EFEQPIYKVQ IPENSPLGSL VATVSARDLD GGANGKISYT LFQPSEDISK TLEVNPMTGE VRLRKQVDFE MVTSYEVRIK ATDGGGLSGK CTLLLQVVDV NDNPPQVTMS ALTSPIAENS PEIVVAVFSV SDPDSGNNGK TISSIQEDLP FLLKPSVKNF YTLVTERALD REARAEYNIT LTVTDMGTPR LKTEHNITVQ ISDVNDNAPT FTQTSYTLFV RENNSPALHI GSVSATDRDS GTNAQVTYSL LPPQDPHLPL ASLVSINADN GHLFALRSLD YEALQAFEFR VGATDRGSPA LSREALVRVL VLDANDNSPL VLYPLQNGSA PCTELVPRAA EPGYLVTKVV AVDGDSGQNA WLSYQLLKAT EPGLFGVWAH NGEVRTARLL SERDAAKQRL VVLVKDNGEP PRSATATLHV LLVDGFSQPF LPLPEAAPGQ TQANSLTVYL VVALASVSSL FLFSVLLFVA VRLCRRSRAA SVGRCSMPEG PFPGRLVDVS GTGTLSQSYQ YEVCLTGGSE TSEFKFLKPI IPNFSP
Target Information
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters.
The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily.
The extracellular domains interact in a homophilic manner to specify differential cell-cell connections.
Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3′ exons as expected.
These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: H00057717-M01_PCDHB16_Q9NRJ7-1_House_mouse.svg, H00057717-M01_PCDHB16_Q9NRJ7-1_House_mouse_PDP.jpeg)
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