Thermo Fisher Scientific CSF2 Monoclonal Antibody (OTI6A3), TrueMAB
인간 CSF2 단백질을 인식하는 단클론 항체로, WB 및 IHC(P) 실험에 적합합니다. 고순도의 액상 형태로 제공되며, 친화 크로마토그래피로 정제되었습니다. PBS, BSA, 글리세롤 기반 완충액에 보관되며, -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6A3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18–144 of human CSF2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at chromosome region 5q31, associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in this cluster include interleukins 4, 5, and 13. The gene promotes tissue inflammation, and elevated cytokine levels have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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