Thermo Fisher Scientific Phospho-Calcitonin Receptor (Ser422, Ser425) Polyclonal Antibody
Calcitonin Receptor의 Ser422/Ser425 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot에 최적화되어 있으며, Human 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태로, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human Calcitonin Receptor (CT) around the phosphorylation site of Ser422/Ser425. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The Calcitonin Receptor inhibits bone resorption and is expressed during development, playing a role in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes. Expression has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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