Thermo Fisher Scientific EDA Monoclonal Antibody (3E12)
EDA 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간 시료에 반응하며, PBS 기반 액상 형태로 제공됩니다. 연구용으로만 사용되며, -20°C에서 보관이 권장됩니다.
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Thermo Fisher Scientific EDA Monoclonal Antibody (3E12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E12 |
| Immunogen | EDA (NP_001390.1, 245–391 a.a.) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ENQPAVVHLQ GQGSAIQVKN DLSGGVLNDW SRITMNPKVF KLHPRSGELE VLVDGTYFIY SQVEVYYINF TDFASYEVVV DEKPFLQCTR SIETGKTNYN TCYTAGVCLL KARQKIAVKM VHADISINMS KHTTFFGAIR LGEAPAS
Target Information
EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. This protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs.
Defects in the gene for EDA are a cause of ectodermal dysplasia, anhidrotic, also known as X-linked hypohidrotic ectodermal dysplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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