Thermo Fisher Scientific Cardiac Troponin I Polyclonal Antibody
심근 트로포닌 I 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트에 반응하며 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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- PA528964
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Thermo Fisher Scientific Cardiac Troponin I Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000–1:10,000
View 1 publication - Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full-length human Cardiac Troponin I recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2546440 |
Product Specific Information
- Recommended positive controls: HepG2, mouse heart
- Predicted reactivity: Mouse (92%), Rat (92%), Dog (94%), Cat (94%), Pig (93%), Bovine (91%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
Cardiac Troponin I (TnI) is an inhibitory protein in cardiac muscle, forming a complex with troponin C (TnC) and troponin T (TnT).
It regulates muscle contraction through calcium-mediated conformational changes.
Blood levels of TnI and TnT serve as diagnostic indicators of cardiac damage and help differentiate between angina and myocardial infarction.
Mutations in the Cardiac Troponin I gene are associated with familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Cardiac Troponin I also inhibits angiogenesis in vivo and in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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