Thermo Fisher Scientific TLE1 Recombinant Rabbit Monoclonal Antibody (TLE1, 2946R)
Recombinant rabbit monoclonal antibody against human TLE1. Optimized for immunohistochemistry on paraffin-embedded tissues. High purity with Protein A/G purification. Supplied as liquid, unconjugated, 1 mg/mL in PBS. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TLE1, 2946R |
| Immunogen | Recombinant human TLE1 fragment (aa 175–338) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Transcriptional corepressor that binds to multiple transcription factors. Inhibits NF-kappa-B-regulated gene expression and transcriptional activation mediated by FOXA2, CTNNB1, and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Also functions as a coactivator for ESRRG.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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