Thermo Fisher Scientific CARD9 Polyclonal Antibody
CARD9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간 단백질에 반응합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5119009
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5–30 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–30 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.01–3 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Caspase Recruitment Domain Family, Member 9 (CARD9), corresponding to amino acid range 26–283 of the target protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903509 |
Target Information
The protein encoded by this gene is a member of the CARD protein family, characterized by the caspase-associated recruitment domain (CARD). CARD domains mediate protein–protein interactions involved in activation or suppression of caspase family members, playing a regulatory role in apoptosis. CARD9 interacts selectively with the CARD domain of BCL10, a positive regulator of apoptosis and NF-κB activation, and functions as a molecular scaffold for assembling a BCL10 signaling complex that activates NF-κB. Several alternatively spliced transcript variants have been observed, though their full-length nature is not clearly defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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