Thermo Fisher Scientific CD52 Monoclonal Antibody (HI186)
인간 CD52 단백질을 인식하는 HI186 클론의 Mouse IgG2b 단일클론 항체입니다. IHC(P) 및 Flow Cytometry에 사용 가능하며, 단백질 A로 정제된 액상형 제품입니다. 면역조절 관련 질환 연구용으로 적합하며, 연구 전용 시약입니다.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 2–10 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 0.5–5 µg/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HI186 |
| Immunogen | Recombinant protein of human CD52 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Thymus
- Cellular Location: Membrane
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein expressed on the surface of various immune cells including T and B lymphocytes, natural killer cells, and monocytes.
It plays a role in immune response regulation and is a therapeutic target in diseases such as multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders.
CD52 is the target of alemtuzumab, a monoclonal antibody used to treat these conditions by depleting CD52-expressing immune cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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