Thermo Fisher Scientific LGN Polyclonal Antibody
Rabbit polyclonal antibody recognizing human LGN (GPSM2) protein. Validated for WB and IP applications. Antigen affinity purified, supplied as liquid at 1 mg/mL. Recommended storage at 4°C. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 450 and 500 of human Mosaic Protein LGN (GPSM2, UniProt ID: P81274-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The LGN (GPSM2) protein belongs to a family of proteins that modulate G protein activation, transducing extracellular signals into cellular responses. Its N-terminal region contains 10 Leu-Gly-Asn repeats, and the C-terminal region contains 4 GoLoco motifs involved in guanine nucleotide exchange. LGN may play a role in neuroblast division and normal hearing development. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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