Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI2C7)
BAG5 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체로, Western blot에 최적화됨. 인간 BAG5 재조합 단백질로 면역화하여 제작됨. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 저장 가능. 연구용으로만 사용.
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- MA527334
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카탈로그
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C7 |
| Immunogen | Full length human recombinant protein of BAG5 produced in 293T |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723966 |
Target Information
It has been hypothesized that the BAG-5 protein induces the death of nigral neurons through its predicted interaction with hsp70, leading to increased protein aggregation and cell death via disinhibition of hsp70’s anti-apoptotic function. BAG-5 may play an important role in neuronal death mechanisms and could act as a modulator of the hsp70/hsp40 chaperone axis. It may also coordinate localization or modulation of other BAG-containing proteins through BAG–BAG heterodimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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