Thermo Fisher Scientific CD85j (ILT2) Monoclonal Antibody (4F9)
CD85j(ILT2)에 특이적인 Mouse IgG1 단클론 항체로, 인간 시료에 반응합니다. IHC(F)와 유세포분석(Flow Cytometry)에 적합하며, 단백질 G로 정제된 액상형 제품입니다. 면역억제 수용체 연구에 유용합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD85j (ILT2) Monoclonal Antibody (4F9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100 |
| Flow Cytometry (Flow) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F9 |
| Immunogen | Monocyte derived dendritic cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745132 |
Product Specific Information
This antibody recognizes CD85j, a member of the leukocyte immunoglobulin-like receptor (LIR) family. CD85j is a receptor for MHC Class I molecules, and ligand binding results in inhibitory signals and down-regulation of the immune response.
Target Information
This gene belongs to the leukocyte immunoglobulin-like receptor (LIR) family, located in the 19q13.4 chromosomal region. The encoded protein is part of the subfamily B class of LIR receptors, containing two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
The receptor is expressed on immune cells, binds to MHC class I molecules on antigen-presenting cells, and transduces a negative signal that inhibits immune stimulation. It is thought to regulate inflammatory responses and cytotoxicity, helping to focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.