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Thermo Fisher Scientific XPF Monoclonal Antibody (OTI2C2), TrueMAB
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ERCC4(XPF) 단백질을 인식하는 Mouse monoclonal antibody(OTI2C2)로 Western blot, ICC/IF, Flow cytometry에 사용 가능. HEK293 세포에서 발현된 full-length recombinant human ERCC4를 면역원으로 제작. 0.85 mg/mL 농도의 액상, PBS/BSA/glycerol buffer에 보관.
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- pk
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마지막 업데이트 2025. 08. 02. 오후 12:40
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Thermo Fisher Scientific TA503341 XPF Monoclonal Antibody (OTI2C2), TrueMAB 100 ul pk판매 단위 pk ·
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600,200원VAT 포함 660,220원
Thermo Fisher Scientific · Thermo Fisher Scientific XPF Monoclonal Antibody (OTI2C2), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C2 |
| Immunogen | Full length human recombinant protein of human ERCC4 produced in HEK293 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.85 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The structure-specific ERCC1/XPF endonuclease complex is involved in repairing two distinct types of DNA lesions:
- Nucleotide excision repair (NER) for UV-induced lesions and bulky chemical adducts
- Recombination repair of genotoxic interstrand cross-links
In NER, dual incisions occur on both sides of the DNA damage, catalyzed by two nucleases. In mammalian cells, XPG cleaves the 3′ side of the lesion, while the ERCC1/XPF complex makes the 5′ incision. ERCC1/XPF also likely participates in processing recombination intermediates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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