Thermo Fisher Scientific PCDHGC5 Polyclonal Antibody
Human PCDHGC5 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 0.75 mg/mL 농도. NT2D1, MCF-7을 양성 대조군으로 권장하며, 인간 및 설치류에 예측 반응성 있음.
- 카탈로그번호
- PA531045
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific PCDHGC5 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 126–416 of Human PCDHGC5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.75 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548519 |
Product Specific Information
- Recommended positive controls: NT2D1, MCF-7
- Predicted reactivity: Mouse (92%), Rat (93%), Chimpanzee (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene belongs to the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome 5. These clusters have an immunoglobulin-like organization, suggesting a novel regulatory mechanism.
The gamma gene cluster includes 22 genes divided into 3 subfamilies:
- Subfamily A: 12 genes
- Subfamily B: 7 genes and 2 pseudogenes
- Subfamily C: 3 genes
Each variable region exon encodes the extracellular region with 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins likely play a critical role in establishing specific neuronal connections in the brain. Alternative splicing has been reported for gamma cluster genes.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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