Thermo Fisher Scientific U2AF1L4 Polyclonal Antibody
U2AF1L4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. ICC/IF에 사용 가능하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 형태로, 장기 보관 시 -20°C에서 보관 권장됩니다.
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Thermo Fisher Scientific U2AF1L4 Polyclonal Antibody
Applications and Tested Dilution
- Immunocytochemistry (ICC/IF): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–202 of U2AF1L4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| RRID | AB_2553314 |
Product Specific Information
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
- Predicted reactivity: Human (99%).
Target Information
RNA-binding protein that functions as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein and protein-RNA interactions required for accurate 3'-splice site selection. Enhances the binding of U2AF2 to weak pyrimidine tracts and regulates alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. Binds RNA at the AG dinucleotide at the 3'-splice site, showing preference for AGC or AGA. [UniProt]
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-36004_U2AF1L4_Q8WU68-1_Rabbit.svg, PA5-36004_U2AF1L4_Q8WU68-1_Rabbit_PDP.jpeg)
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