Thermo Fisher Scientific PTX3 Monoclonal Antibody (03)
Human PTX3/Pentraxin 3/TSG-14에 특이적인 단클론 항체로 ELISA에 적합. Mouse IgG1 형식이며 비결합 상태로 제공. 1 mg/mL 농도의 액상 제품으로 단백질 A 정제. -20°C 보관, 동결/해동 반복 피해야 함.
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Applications
ELISA
- Tested Dilution: 1:250–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 03 |
| Immunogen | Recombinant Human PTX3/Pentraxin 3/TSG-14 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912172 |
Product Specific Information
- Specificity: Human PTX3/Pentraxin 3/TSG-14
Target Information
Pentraxins are a protein superfamily characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that plays a non-redundant role in resistance to selected microbial agents.
Ptx3 belongs to the family of long pentraxins, which have C-terminal pentraxin domains and novel amino-terminal domains. It binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa, and Salmonella typhimurium.
It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF. Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity.
The human PTX3 gene maps to chromosome 3q25.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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