Thermo Fisher Scientific NFkB p65 Recombinant Rabbit Monoclonal Antibody (23GB1490)
NFkB p65 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, 유세포분석에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 고순도 친화 크로마토그래피 정제 및 안정한 글리세롤 보존 용액 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB1490 |
| Immunogen | A synthesized peptide derived from human NF-kB p65 (500–551AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and located on human chromosome 11. NF-kB p65, also known as RelA, belongs to the Rel family of proteins and is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells), forming heterodimers with p50 or p52. Upon TNF alpha stimulation, IKK phosphorylates IκB, leading to its degradation and activation of NF-kB p65. This protein plays an essential role in transcriptional regulation of immunoglobulin kappa genes in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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