Thermo Fisher Scientific WBP1L Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human WBP1L. Recombinant protein control fragment (Product #RP-97171). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:WBP1L,uniProtId:Q9NX94-1,ncbiNodeId:9606,antigenRange:160-249,antigenLength:342,antigenImageFileName:PA5-58038_WBP1L_Q9NX94-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58038_WBP1L_Q9NX94-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649531

Product Specific Information

Immunogen sequence: PLSEPSRSST RPPSIADPDP SDLPVDRAAT KAPGMEPSGS VAGLGELDPG AFLDKDAECR EELLKDDSSE HGAPDSKEKT PGRHRRFTGD

Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 76%.

Target Information

WBP1L (OPAL1, outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megakaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.