Thermo Fisher Scientific Cholera Toxin beta Polyclonal Antibody, FITC

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1:10-1:50

-

Product Specifications

Species Reactivity

Bacteria

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Purified Choleragenoid.

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra

Form

Liquid

Concentration

4-5 mg/mL

Purification

IgG fraction

Storage buffer

PBS, pH 7.2, with 10mg/mL BSA

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1016848

Product Specific Information

The PA1-73188 antibody reacts with Cholera toxin beta subunit.

PA1-73188 has been successfully used in Immunofluorescence applications.

The PA1-73188 antibody was raised against purified Choleragenoid.

Target Information

Cholera toxin (sometimes abbreviated to CTX, Ctx, or CT) is a protein complex secreted by the bacterium Vibrio cholerae. CTX is the causative agent of cholera infection. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.