Thermo Fisher Scientific TNN Polyclonal Antibody
Human TNN 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 1:50–1:200 희석 비율로 검증됨. 항원 친화 크로마토그래피로 정제된 액상 항체. 세포 이동 및 신경돌기 성장 연구에 적합. 연구용으로만 사용 가능.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TNN. Recombinant protein control fragment (Product # RP-94146) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648788 |
Product Specific Information
Immunogen sequence:
GTKYIVTLRN VKNEVSSSPQ HLLATTDLAV LGTAWVTDET ENSLDVEWEN PSTEVDYYKL RYGPMTGQEV AEVTVPKSSD PKSRYDITGL HPGTEYKITV V
Antigen sequence identity:
- Mouse: 88%
- Rat: 88%
Target Information
Extracellular matrix protein that acts as a ligand for ITGA8:ITGB1, ITGAV:ITGB1, and ITGA4:ITGB1 (PubMed:17909022).
Involved in neurite outgrowth and cell migration in hippocampal explants.
During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts via canonical WNT signaling.
In tumors, promotes angiogenesis by elongation, migration, and sprouting of endothelial cells (PubMed:19884327).
Highly expressed in mammary tumors and may facilitate tumorigenesis by supporting migratory behavior of breast cancer cells (PubMed:17909022).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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