Thermo Fisher Scientific APOL3 Monoclonal Antibody (4E5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

4E5

Immunogen

APOL3 (NP_663615, 240 a.a. approximately 336 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Apolipoprotein L3,uniProtId:O95236-1,ncbiNodeId:9606,antigenRange:240-336,antigenLength:402,antigenImageFileName:H00080833-M01A_Apolipoprotein_L3_O95236-1_House_mouse.svg,antigenImageFileNamePDP:H00080833-M01A_Apolipoprotein_L3_O95236-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: VEHSYTSSAE AEASRLTATS IDRLKVFKEV MRDITPNLLS LLNNYYEATQ TIGSEIRAIR QARARARLPV TTWRISAGSG GQAERTIAGT TRAVSRG

Target Information

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL1-6, which are associated with large high density type lipoproteins (HDL). The human apoL family maps to chromosome 22q12.1-13.1 within a 127,000 bp region. apoL2 and apoL3 may allow the binding of lipids to organelles or may be involved in the movement of lipids in the cytoplasm. apoL2 localizes to the cytoplasm and is widely expressed, with the highest levels observed in the lung, thymus, pancreas, placenta, adult brain and prostate. The apoL2 protein is also detected in the spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea, mammary gland, skeletal muscle, testis and fetal brain and liver. apoL3 also localizes to the cytoplasm and is widely expressed, with highest levels detected in the prostate, lung and placenta. It is also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland. Lower levels of apoL3 are observed in the brain, heart, fetal liver, pancreas and testis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.