Thermo Fisher Scientific APOL3 Monoclonal Antibody (4E5)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
VEHSYTSSAE AEASRLTATS IDRLKVFKEV MRDITPNLLS LLNNYYEATQ TIGSEIRAIR QARARARLPV TTWRISAGSG GQAERTIAGT TRAVSRG

Target Information

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL1–6, which are associated with large high-density lipoproteins (HDL). The human apoL family maps to chromosome 22q12.1–13.1 within a 127,000 bp region.

apoL2 and apoL3 may enable lipid binding to organelles or be involved in lipid movement in the cytoplasm. apoL2 localizes to the cytoplasm and is widely expressed, with highest levels in lung, thymus, pancreas, placenta, adult brain, and prostate. It is also detected in spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea, mammary gland, skeletal muscle, testis, and fetal brain and liver.

apoL3 localizes to the cytoplasm and is widely expressed, with highest levels in prostate, lung, and placenta. It is also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea, and mammary gland. Lower levels are observed in brain, heart, fetal liver, pancreas, and testis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.