Thermo Fisher Scientific CXCL11 Monoclonal Antibody (10C6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

ELISA (ELISA)

1-3 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

10C6

Immunogen

Full length recombinant protein expressed in E-Coli if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CXCL11,uniProtId:O14625-1,ncbiNodeId:9606,antigenRange:1-94,antigenLength:94,antigenImageFileName:MA1032_CXCL11_O14625-1_House_mouse.svg,antigenImageFileNamePDP:MA1032_CXCL11_O14625-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.0 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2536717

Product Specific Information

MA1032 has successfully been paired as the coating antibody in a sandwich ELISA with detection antibody MA1033B (biotinylated conjugate of clone 22F1).

Typical dilutions for sandwich ELISA include 1 µg/mL for coating and 0.125-0.25 µg/mL for detection.

The Molecular weight is ~8303 Da from positions 22 - 94 as determined by MALDI.

Target Information

Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.