
Thermo Fisher Scientific Spastin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Spastin protein. Validated for Western blot applications. High specificity with multiple species homology. Supplied as liquid form, affinity purified, stored at -20°C. For research use only.
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Thermo Fisher Scientific Spastin Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1 µg/mL
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SPAST |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576767 |
Product Specific Information
Peptide sequence:
RVLVMGATNR PQELDEAVLR RFIKRVYVSL PNEETRLLLL KNLLCKQGSPSequence homology:
Cow: 100%
Dog: 100%
Goat: 93%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 100%
Target Information
This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this family share an ATPase domain and are involved in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis.
The encoded ATPase may participate in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full-length sequences have not been determined.
Mutations in this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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