Thermo Fisher Scientific PMCA1 ATPase Polyclonal Antibody
PMCA1 ATPase를 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체입니다. Western blot에 최적화되어 있으며, 인간 시료에 반응합니다. 액상 형태로 제공되며, TBS 버퍼에 BSA와 sodium azide가 포함되어 있습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5142821
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.03–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KQDGAIENRNKAKAQD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933464 |
Product Specific Information
- Expected to recognize both reported isoforms (NP_001001323.1; NP_001673.2).
- Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
The calcium pump of the plasma membrane, termed PMCA ATPase, pumps calcium from the cytosol to the extracellular space. This membrane-bound enzyme is related to other ATPases including SERCA ATPase and the sodium/potassium pump.
There are four different genes encoding PMCA ATPase, and 20 isoforms are generated by alternative splicing.
mRNA distribution studies show:
- Gene products 1 and 4 are transcribed in most tissues.
- Products 2 and 3 are more tissue-specific.
- In the pancreas, beta cells express only the 4b isoform, while alpha and gamma cells express both 4a and 4b isoforms.
Different splice variants have varying affinities for calcium and calmodulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-142821_PMCA1_ATPase_P20020-3_Goat.svg, PA5-142821_PMCA1_ATPase_P20020-3_Goat_PDP.jpeg)
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