Thermo Fisher Scientific H2BK116me1 Recombinant Rabbit Monoclonal Antibody (3R10S2)
Histone H2B K116 단일메틸화(H2BK116me1)를 인식하는 재조합 토끼 단클론 항체. IHC(P) 및 ELISA에 적합하며, 인간, 마우스, 랫트 반응성. 고순도 Protein A 정제, 50% 글리세롤 함유 PBS 완충액에 보관. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3R10S2 |
| Immunogen | A synthesized peptide derived from human Histone H2B (mono methyl K116) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of H2A, H2B, H3, and H4. This structure compacts DNA into chromatin, limiting DNA accessibility to transcription, replication, and repair machinery. Histone H2B also exhibits broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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