
Thermo Fisher Scientific C21orf37 Polyclonal Antibody
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Applications
Tested Dilution
Publications
Immunohistochemistry (Paraffin) (IHC (P))
1:200-1:400
Immunohistochemistry (Frozen) (IHC (F))
1:100-1:500
Immunocytochemistry (ICC/IF)
1:100-1:500
ELISA (ELISA)
1:500-1:1,000
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human C21orf37.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
C22orf37 (chromosome 22 open reading frame 37), also known as FLJ40542, is a 170 amino acid protein encoded by a gene located on human chromosome 22, which contains over 500 genes and about 49 million bases. As the second smallest human chromosome, chomosome 22 contains a wide variety of genes with numerous functions. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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