Thermo Fisher Scientific ABHD4 Polyclonal Antibody
ABHD4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. IHC(P)에서 1:50–1:100 희석으로 사용 가능. 인간 ABHD4 유래 합성 펩타이드 면역원. 액상 형태, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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- PA538998
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human ABHD4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555590 |
Target Information
The α/β hydrolase superfamily consists of diverse members involved in important biochemical processes and various diseases. Despite having unrelated sequences, different substrates, and distinct catalytic activities, they share a canonical α/β hydrolase fold with an eight-stranded parallel α/β structure and a catalytic triad composed of histidine, acid, and nucleophile residues.
Members of this superfamily serve as potential drug targets for diseases such as diabetes, Alzheimer’s disease, obesity, and blood clotting disorders.
- ABHD1: Metabolizes smoking xenobiotics
- ABHD2: Participates in atherosclerosis development
- ABHD4: Functions as a lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE), involved in N-acyl ethanolamine biosynthesis
- ABHD5: Mutations linked to Chanarin-Dorfman syndrome
- ABHD6: May play a role in nervous system metabolism and signaling
- ABHD14A: Possibly involved in granule neuron development
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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