Thermo Fisher Scientific KLK3 Monoclonal Antibody (OTI2A2), TrueMAB
인간 KLK3(PSA) 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot 및 IHC(P) 검증 완료. 동결건조 상태로 제공되며, PBS 버퍼와 trehalose 포함. 연구용으로 PSA 관련 단백질 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 25–261 of human KLK3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Prostate-specific antigen (PSA) is a chymotrypsin-like serine protease belonging to the kallikrein family, produced by the prostate epithelium and abundant in seminal fluid.
PSA can be detected in the sera of patients with prostatic carcinoma, where it is predominantly complexed to alpha-1-antichymotrypsin (ACT).
A higher proportion of PSA-ACT complex is found in prostate cancer compared to benign prostatic hyperplasia.
PSA serves as a marker to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to differentiate from non-prostatic carcinoma mimics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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