
Thermo Fisher Scientific Human ORMDL1 Synthetic Peptide
인간 ORMDL1 단백질의 중심부 16개 아미노산 서열로 구성된 합성 펩타이드입니다. 항체 PA5-21146의 블로킹 펩타이드로 사용 가능하며, 순도 높은 액상 형태로 제공됩니다. 알츠하이머병 및 천식 관련 연구에 활용됩니다.
- 카탈로그번호
- PEP1260
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the center of human ORMDL1.
PEP-1260 can be used as a blocking peptide with polyclonal antibody PA5-21146.
Target Information
The ORMDL (ORM1-like) family of proteins consists of ORMDL1, ORMDL2, and ORMDL3, which may play roles in γ-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and implicated in the expression of Presenilin (PSI), a protein involved in Alzheimer’s disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have also been identified as potential risk factors for childhood asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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