Thermo Fisher Scientific Lefty1/Lefty2 Recombinant Rabbit Monoclonal Antibody (ARC2149)
Lefty1/Lefty2 단백질을 인식하는 재조합 토끼 단일클론 항체로, WB, IHC, ELISA에 적합합니다. 인간, 마우스, 랫트 반응성. HEK293 세포 발현, 액상형 항체이며 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2149 |
| Immunogen | Synthetic peptide corresponding to amino acids 267–366 of human LEFTY1/2 (O75610) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.3) with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897962 |
Product Specific Information
- Positive Samples: HT-29, BxPC-3, Mouse brain, Rat brain
- Immunogen sequence:
EMYIDLQGMK WAENWVLEPP GFLAYECVGT CRQPPEALAF KWPFLGPRQC IASETDSLPM IVSIKEGGRT RPQVVSLPNM RVQKCSCASD GALVPRRLQP
Target Information
Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis.
Lefty1 acts as a regulator of Lefty2 and NODAL, as the lack of Lefty1 results in bilateral expression of nodal, lefty2, and Pitx2 (a homeobox gene normally expressed on the left side).
Lefty2 may play a role in endometrial bleeding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-38044_Lefty1Lefty2_O00292-1_Rabbit.svg, MA5-38044_Lefty1Lefty2_O75610-1_Rabbit.svg 등)
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