Thermo Fisher Scientific Phospho-mTOR (Ser2481) Polyclonal Antibody
Human mTOR 단백질의 Ser2481 위치 인산화 상태를 검출하는 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 높은 특이성과 재현성을 제공. 항원 친화 크로마토그래피로 정제된 액상 형태로, 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-mTOR (Ser2481) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human mTOR (phospho Ser2481). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736392 |
Product Specific Information
- Positive Control:
- 293T (Starvation 24 hr)
- 293T (Starvation 24 hr + 200 ng/mL EGF treatment for 30 min)
- Predicted Reactivity: Mouse (100%), Rat (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene result in Smith-Kingsmore syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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