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Thermo Fisher Scientific XPF Monoclonal Antibody (OTI2D4), TrueMAB
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Thermo Fisher Scientific XPF Monoclonal Antibody (OTI2D4), TrueMAB

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ERCC4(XPF) 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot, ICC/IF, Flow cytometry 등에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 -20°C에서 보관. DNA 손상 복구 관련 연구용으로 적합.

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TA503063
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오전 06:46
Thermo Fisher Scientific TA503063 XPF Monoclonal Antibody (OTI2D4), TrueMAB 100 ul pk판매 단위 pk ·
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600,200원VAT 포함 660,220원

Thermo Fisher Scientific · Thermo Fisher Scientific XPF Monoclonal Antibody (OTI2D4), TrueMAB

Applications

Western Blot (WB)

  • Tested Dilution: 1:2,000

Immunocytochemistry (ICC/IF)

  • Tested Dilution: 1:100

Flow Cytometry (Flow)

  • Tested Dilution: 1:100

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Clone OTI2D4
Immunogen Full length human recombinant protein of human ERCC4 produced in HEK293T cell
Conjugate Unconjugated
Form Liquid
Concentration 0.77 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of DNA lesions:

  • NER (Nucleotide Excision Repair) for UV-induced lesions and bulky chemical adducts
  • Recombination repair of genotoxic interstrand cross-links

In mammalian cells, XPG cleaves the 3′ side of the DNA lesion, while the ERCC1/XPF complex makes the 5′ incision.
ERCC1/XPF likely plays a role in processing partially repaired recombination intermediates.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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