Thermo Fisher Scientific Calpain 12 Polyclonal Antibody
Calpain 12 단백질을 검출하는 토끼 폴리클로날 항체. Western blot에 적합하며 사람 및 생쥐 시료에서 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, PBS와 글리세롤 완충액에 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human CAPN12 (aa 221–270) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635447 |
Product Specific Information
This antibody detects endogenous levels of total CAPN12 protein.
Target Information
Calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that function as nonlysosomal, intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes are heterodimers composed of distinct large catalytic subunits associated with a common small regulatory subunit.
The CAPN1 gene encodes the large subunit of the ubiquitous enzyme calpain 1. Several transcript variants encoding two different isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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