Thermo Fisher Scientific RND2 Polyclonal Antibody
RND2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat에 반응하며, 친화 크로마토그래피로 정제된 액상 형태입니다. PBS/glycerol 버퍼에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RND2 (Accession P52198), corresponding to amino acid residues S166–I216 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853437 |
Product Specific Information
Antibody detects endogenous levels of total RND2.
Target Information
The Ras p21 family of guanine nucleotide proteins has been widely studied for its role in signal transduction and high mutation frequency in human malignancies. Ras proteins (H-, K-, and N-Ras p21) are part of a larger superfamily of related proteins. Members such as Rap1A, Rap1B, Rap2, R-Ras, RalA, and RalB share approximately 50% amino acid homology with Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7, and 8) are about 30% homologous to Ras and are expressed in various cell types. Both Ras p21 and Rho p21, as well as other Ras superfamily members, contain a carboxy-terminal CAAX sequence (C: cysteine; A: aliphatic amino acid; X: any amino acid), which is essential for proper localization and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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