Thermo Fisher Scientific CEA (CEACAM5) Monoclonal Antibody (OTI1C2), TrueMAB
Human CEACAM5(CD66e) 단백질을 인식하는 Mouse IgG2b 단클론 항체로 Western blot과 IHC(P)에서 검증됨. 비접합 형태이며 높은 특이성과 재현성을 제공. 종양 표지자 연구 및 대사성 암 진단 연구용에 적합.
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Thermo Fisher Scientific CEA (CEACAM5) Monoclonal Antibody (OTI1C2), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–680 of human CEACAM5 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
CEA (Carcino Embryonic Antigen, CD66e) is synthesized during development in the fetal gut and re-expressed in increased amounts in intestinal carcinomas and other tumors. It belongs to the immunoglobulin supergene family and consists of one N domain and six immunoglobulin constant-like domains. Antibodies to CEA are useful for identifying the origin of metastatic adenocarcinomas and distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.
CEA functions as a cell adhesion molecule found on leukocytes, epithelia, and endothelia, mediating homophilic and heterophilic interactions. It plays roles in tissue differentiation, angiogenesis, apoptosis, tumor suppression, metastasis, and immune response modulation. Multiple transcript variants exist, though not all are fully defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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