Thermo Fisher Scientific MEI-1 Polyclonal Antibody
MEI-1 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트에서 반응. WB, IHC, ICC, ELISA 등 다양한 응용 가능. Protein A로 정제된 액상 형태, -20°C 보관. 생식세포 분열 연구 및 불임 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MEI-1 (amino acids 266–370) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MEI1 (Meiosis inhibitor protein 1), also known as Meiosis defective protein 1, is a 1274 amino acid protein required for the formation of genetically programmed double-strand breaks, the first step in meiosis initiation. It is predominantly expressed in testis, and defects in the MEI1 gene are associated with male infertility. Genetic variation in MEI1 may predispose certain populations to infertility by meiotic arrest. Human MEI1 shares 79% sequence similarity with its mouse homolog, and seven isoforms are produced via alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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