Thermo Fisher Scientific GW182 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human GW182 (TNRC6A) protein. Validated for WB and IP applications. Supplied as liquid, unconjugated, 1 mg/mL concentration. Recommended storage at 4°C, shipped on wet ice. For research use only.
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Applications
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 6 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 575 and 625 of human glycine-tryptophan protein of 182 kDa (TNRC6A, UniProt ID: Q8NDV7-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
TNRC6A is a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. It associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.
Publication Note: This RefSeq record includes a subset of the publications available for this gene. Please refer to the Entrez Gene record for additional references.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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