
Thermo Fisher Scientific TXNRD1 Monoclonal Antibody (OTI7B2), TrueMAB
TXNRD1 단백질을 인식하는 마우스 단클론 항체로, WB 및 IHC(P) 검증 완료. 인간, 생쥐, 랫트 반응성. 고순도 액상 형태로 1 mg/mL 농도. 산화 스트레스 및 셀레늄 대사 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7B2 |
| Immunogen | Full-length human recombinant protein of human TXNRD1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. The protein reduces thioredoxins and other substrates, playing a key role in selenium metabolism and protection against oxidative stress.
The functional enzyme is a homodimer that uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue essential for catalytic activity.
Selenocysteine is encoded by the UGA codon, typically a stop signal, but recognized as Sec through a SECIS element in the 3′ UTR.
Alternative splicing yields multiple transcript variants encoding identical or distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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