Thermo Fisher Scientific GRPR Recombinant Rabbit Monoclonal Antibody (18H31L38)
GRPR 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체로, IHC 및 ICC/IF 실험에 적합. 인간에 반응하며 마우스, 랫, 소에도 예측 반응. 단백질 A로 정제된 액상 항체로 안정적이고 재현성 높은 결과 제공.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 18H31L38 |
| Immunogen | Peptides corresponding to human GRPR [aa364-aa384, aa4-aa19] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2895891 |
Product Specific Information
This antibody is predicted to react with Mouse, Rat, and Bovine.
Target Information
Gastrin-releasing peptide (GRP) regulates various functions of the gastrointestinal and central nervous systems, including hormone release, smooth muscle contraction, and epithelial proliferation. GRP acts as a potent mitogen for neoplastic tissues through the gastrin-releasing peptide receptor (GRPR), a glycosylated 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. GRPR is aberrantly expressed in cancers such as lung, colon, and prostate. A balanced translocation between chromosome 8 and X involving the GRPR gene has been observed in a patient with autism and multiple exostoses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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