Thermo Fisher Scientific BCL2L15 Polyclonal Antibody
Thermo Fisher Scientific의 BCL2L15 Polyclonal Antibody는 인간 BCL2L15 단백질을 인식하는 Rabbit IgG 항체로, WB, IHC, ICC/IF에 사용 가능. 고순도 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 1 mg/mL 농도. 연구용으로만 사용.
- 카탈로그번호
- PA522139
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific BCL2L15 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length human BCL2L15 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154253 |
Product Specific Information
- Recommended positive control: Raji
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Proteins of the Bcl-2 family are critical regulators of apoptosis. Proapoptotic members, such as Bax, contain three of the four Bcl-2 homology regions (BH1–3), while BH3-only proteins, like Bim, possess only the short BH3 motif. Database searches revealed Bfk, a novel member of the Bcl-2 family containing BH2 and BH3 regions but lacking BH1 and BH4. Bfk is closely related to Bcl-G(L), lacks a C-terminal membrane anchor, and is cytosolic. Overexpression of Bfk weakly promotes apoptosis and antagonizes Bcl-2’s prosurvival function. Bfk does not bind other Bcl-2 family members, though its BH3 motif can mediate association with prosurvival proteins. Low levels of Bfk are found in stomach, ovary, bone marrow, and spleen, with increased expression in mammary gland during pregnancy, suggesting a role in mammary development.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
제품 이미지
(이미지 파일: PA5-22139_BCL2L15_Q5TBC7-1_Rabbit.svg, PA5-22139_BCL2L15_Q5TBC7-1_Rabbit_PDP.jpeg)
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